At the opening of Katerynoslavsk Mining College Professor Kurilov V.V. created a laboratory of General Chemistry for the education of mining engineers in Chemical disciplines. Originally, it was located in the house of the former Potemkin Palace, and then from 1907, it was moved to building No. 2 (Chemical). Laboratories of qualitative, quantitative and mining analysis were organized there.

The Laboratory of Physical Chemistry was founded in 1913-1914 by Lev Volodymyrovich Pisarzhevskii (who was a Head of the laboratory of General Chemistry, Qualitative Analysis and Physical Chemistry), and Yu. V. Korshun, (who was a Head of the laboratories of Qualitative and Rock Analysis. Then, he headed the Department of Organic and Analytical Chemistry). Kurilov V.V. and Pisarzhevskii L.V. were the organizers of the Chemical Department.

Delivered chemical lectures and headed the department:

Venedikt Viktorovych Kurilov (1867-1921) graduated the Kazan University in 1899, Doctor of Chemistry, Professor of the Department of General Chemistry, worked at Katerynoslavsk Mining Institute in 1899-1911, headed the Department of General Chemistry in 1901-1911.

Olexander Mykolayovych Shchukarev (1864-1936) graduated the Moscow University in 1899, Professor (1912), headed the Department of General Chemistry in 1911-1913.

Lev Volodymyrovich Pisarzhevskii (1874-1938) graduated the Chemical Department of the Physics and Mathematics Faculty of Novorossiysk University, Professor of General and Physical Chemistry and Head of the Department of Chemistry in 1913-1932, Rector of the Katerynoslavsk Mining Institute in 1923-1926, Honored Professor (1925) Member of the Ukrainian SSR Academy of Sciences, Director of the Ukrainian Institute of Physical Chemistry (1927), Associable of the Academy of Sciences (1928), Full Member of the Ukrainian SSR Academy of Sciences (1930).

Dmitro Petrovych Konovalov (1856-1929) graduated the St. Petersburg University in 1878, Professor (1886), Full Member of the Ukrainian SSR Academy of Sciences (1932), worked at the Dnipropetrovsk Mining Institute in 1918-1922 at the Department of Chemistry. Director of the Chemical and Energy Institute (Dnipropetrovsk) in 1919-1922.

Yurii Vasyliovych Korshun (1873-1951), Master of Chemistry, Professor, headed the Laboratories of Qualitative and Rock Analysis and headed the Department of Organic and Analytical Chemistry in 1922-1930.

Klara Volodymirivna Roll (1877-1958) graduated the University of Geneva (Switzerland) in 1904, Doctor of Chemical Sciences (1905), Professor (1928), worked at the Dnipropetrovsk Mining Institute in 1922-1930.

Olexander Ilych Brodskii (1895-1969) studied at the Dnipropetrovsk Mining Institute from 1913 and worked in the Pisarzhevskii Laboratory. He went to MSU from the third year and graduated in 1922. Professor of the Dnipropetrovsk Mining Institute (1925), Head of the Departments of Physical Chemistry at the  Dnipropetrovsk Mining Institute, Dnipropetrovsk Chemical and Technology Institute, Dnipropetrovsk Metallurgical Institute in 1930-1941, Academician of the Academy of Sciences of Ukraine (1939), Director of the Pisarzhevskii Institute of Physical Chemistry in 1939-1959, Associable Member of the Ukrainian SSR Academy of Sciences (1943).

Yakiv Yosypovych Gabinskii, mining engineer. He graduated the Katerynoslavsk Mining Institute in 1917, a studied under the supervision of Professor Rubin, Assistant in Metallurgy since 1918, Professor (1927), Head of the Faculty of Chemical Technology, Doctor of Chemical Sciences (1930), later worked at Dnipropetrovsk Chemical and Technology Institute, Giprokoks (Kharkiv), Carbochemisty Institute (Kharkiv), Kharkiv Chemical Institute of Technology.

Mykhailo Volodymyrovych Polyakov (1893-1965), chemist-teacher, graduated the Dnipropetrovsk Institute of Public Education in 1923, Professor (1934), worked at the Dnipropetrovsk Mining Institute in 1928-1941, Headed the Department of General Chemistry up to 1943.

Kondrat Kyrylovych Grianenko was born in 1900. He was a lecturer in the chemical disciplines, graduated the Dnipropetrovsk Institute of Public Education in 1927, an Associate Professor (1940), worked at the Dnipropetrovsk Mining Institute from 1934 to 1948.

Mykhailo Mykytovych Chechenkin (was born in 1889), was a chemistry teacher, graduated the Natural History Faculty of Smolensk State University in 1925, Assistant Professor (1943), Head of the Department of Chemistry in 1943-1948.

Valentina Olexandrivna Alexeeva (1898-1972), was a teacher of chemical disciplines, graduated the Chemical Department of the Dnipropetrovsk Institute of Public Education in 1924, worked at the Dnipropetrovsk Mining Institute in 1927-1971, Head the Department of Chemistry in 1948-1959.

Leonid Volodymyrovich Korchagin (1907-1991), was a chemist-teacher, graduated the Chemical Department of the Dnipropetrovsk Physics, Chemistry and Mathematics Institute in 1932, Associate Professor (1954), worked at the Dnipropetrovsk Mining Institute in 1954-1975, Head the Department of Chemistry in 1959-1970.

Tetyana Prokopivna Dorosh (1921-2001), was chemical engineer, graduated the Chemical Faculty of Dnipropetrovsk State University in 1947, Candidate of Technical Sciences (1963), Associate Professor (1964), worked at the Dnipropetrovsk Mining Institute in 1962-1982, Head the Department of Chemistry in 1970-1980.

Nina Olexandrivna Tymchenko (was born in 1929), was a chemical engineer, graduated the Chemical Faculty of Dnipropetrovsk State University in 1953, Candidate of Chemical Sciences (1969), Associate Professor (1970), worked at the Dnipropetrovsk Mining Institute in 1964-1995.

Pavlo Olexiyovych Yegorov (20.04.1941-06.04.2016), was a chemist-technologist, graduated the Dnipropetrovsk Metallurgical Institute in 1963, Candidate of Chemical Sciences (1968), Associate Professor (1970), worked at the Dnipropetrovsk Mining Institute in 1963-2015. Head of Department in 1980- 2015.

Olena Yuriivna Svietkina (was born in 1959), chemical engineer, graduated the Dnipropetrovsk State University in 1981, Candidate of Chemical Sciences (1985), Associate Professor (1990), defended her doctoral thesis in 2015, since 2015 Head of the Department.

Chemical disciplines at the Department of Chemistry were delivered by Associate Professors V.L. Masalskii (1952-1953), V.I. Mozgovii (1945-1984), M.I. Dedusenko (1960-1972), I.Y. Mnushkin (1965-1998), T. V. Zegzhda (1969-1994), O.I. Temchenko (1982-2015), V.D. Meshko (1982-2015), I.G. Shatukhin (1982-1987), S.M. Lysytska (since 2009), Senior teachers M.I. Milkovskii (1945-1966), O.M. Popov (1967-1997), O.B. Netyaga (since 1985), Assistants T.F. Borshchevska (1952-1977), Ye.S. Lukyanenko (1962-1967), V.I. Shishlevska (1968-1994), S.O. Chudnii (1979-1980), I.V. Romanova (1995-2000), H.V. Tarasova (since 2000), O.V. Polulyakh (2007-2017).